Calculator for screening of advanced fibrosis in MASLD version 1.05 This FIB-9 calculator requires 4 clinical data and 9 blood markers part of the usual liver function tests. However, urea can be omitted. 1. Single Computation If you have only one computation to perform, use the following form. If you have more than one, see «Multiple Computations» below. This calculator requires 4 clinical data and 9 blood markers part of the usual liver function tests. Mandatory Variables Values Units Accepted Range Age      Years   18-90   Weight      kg   40-180   Height      m   1.2-2   Diabetesa    No/Yes No/Yes AST      IU/l   10-300   ALT      IU/l   10-400   GGT      IU/l   10-1000   Alkaline phosphatases      IU/l   10-300   Bilirubin      μmol/l   2-600   Albumin      g/l   12-70   Platelets      G/l   30-550   Prothrombin Index or       %   20-150   INRb      None   0.6-4   Ureac or       mmol/l   1-14   Sexc      F=0, M=1   0-1     a   Two fasting blood glucose ≥ 1.26 g/l or diabetes treatment b   If your input variable is INR, it will automatically be converted to « Prothrombin Index (%) » according to a specific formula issued from (5) : 5. Cales P, Tuffigo M, Oberti F, Planche V, Boursier J, Fouchard Hubert I, et al. Clinical comparison and conversion of international normalized ratio and prothrombin index. J Hepatol 2019; 70: e814-e815. c   If Urea data is not provided, you must give a value to the Sex data and a FIB-8 score will be computed instead of a FIB-9 score.                   reset  Examples         example 1          example 2          example 3          example 4          example 5            example 6          example 7          example 8          example 9          example 10    Results: FIB-9 ???? urea score is ??? It expresses the probable fibrosis stage according to Kleiner F system (0 to 4). Advanced fibrosis is Comment #1: The accuracy estimation is not provided for that FIB-8 test. FIB-9 reliability: Acuracy estimation: ??? Comment #2: Etoile Accuracy (% of correct classification for FIB-9 score value) is estimated according to the following Figure. Figure: Accuracy estimation of FIB-9 score (Y axis) into 9 classes as a function of growing value from 0 to 4 (X axis). The % indicates the class prevalence in the original data base (1051 patients with NAFLD). 2. Multiple Computations with urea available     Copy your dataset from your Excel file and paste in the yellow area below.     The columns in your Excel file must be in the variable order of the previous table.     Likewise, the units are the same while diabetes must be coded as 0 (no) or 1 (yes).     State the index used for Quick time:       ☑   INR values         ☐   Prothombin Index values   If your input variable is INR, it will automatically be converted to « Prothrombin Index (%) » according to a specific formula issued from (5) : 5. Cales P, Tuffigo M, Oberti F, Planche V, Boursier J, Fouchard Hubert I, et al. Clinical comparison and conversion of international normalized ratio and prothrombin index. J Hepatol 2019; 70: e814-e815. Click  here  only when urea is unavailable. In that case, the last column includes the sex value (instead of urea) with the following code for sex: 0 for Female, 1 for Male.     Click on the  compute  button under your data to retrieve the FIB-9 test results.           example 1     example 2     example 3     example 4     example 5     example 6     reset  Click  here  to return to the main page for this calculator. Calculator created by Gilles Hunault. Author responsible for this content: Pr. Paul CALÈS, Angers University (France). ORCID: https://orcid.org/0000-0003-4866-5274 Version date: January 2025.

 

 

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